GMO Feeding Studies

This post introduces our infographic about GMO feeding studies.

Laboratory mouse by Rama via Wikimedia.
Laboratory mouse by Rama via Wikimedia.

Proper experimental design is the foundation of any scientific publication. However, a study is not so easy to plan, particularly when it includes methods that are expensive or that use tools that are hard to find. To make things more complicated, many studies are performed as part of a Master’s or Doctoral thesis, and the investigator gains skills and knowledge throughout the course of the experiment. By the time the study is done, the investigator sees parts she would have done differently.
Studies that involve animals are especially complex, since you cannot “redo” a failed experiment as easily as you can with in vitro or in silico assays. Criticisms by reviewers and editors can seldom be addressed during the peer review process: if an editor or reviewer identifies a flaw in an animal feeding study, it often cannot be redone due to resource constraints.
Poorly designed GMO feeding studies abound, quite possibly due to these difficulties in performing any animal feeding study. Such studies are often used by people who claim GMO are dangerous. It can be difficult to determine if a study has been properly designed and performed. We’ve put together a list to help you navigate through the messy world of GMO feeding studies.
Continue reading “GMO Feeding Studies”

GMOs and Patents: Part 3 – Lawsuits for inadvertent contamination

lawsuits against farmers

This is the third and final post in a series examining the topic of GMOs and patents. The first post provided an overview on the topic of patents and described the concept of “terminator genes”. The second post examined lawsuits against farmers for using genetically modified seeds, focusing on two high profile cases (Schmeider v Monsanto, and Bowman v Monsanto). This final post will examine whether there have been cases of lawsuits brought against farmers for unknowingly using GE seeds or inadvertent contamination.

This paragraph from the previous post in the series must be repeated here: “Most of this article will focus on Monsanto, primarily because it has been the target of many activist efforts (I have yet to see a March Against Syngenta). As you may know, the commonly repeated myth is that Monsanto has taken hundreds of farmers to court for inadvertent contamination or for replanting GE seeds. According to the company’s website, there have been ‘147 lawsuits filed since 1997 in the United States. This averages about 8 per year for the past 18 years. To date, only 9 cases have gone through full trial. In every one of these instances, the jury or court decided in our favor.'”

To determine if any of these cases was unfairly brought against a farmer (inadvertent contamination or unknowingly using GE seeds), I would have had to review each of these cases. However, I came across a story that had done all the work for me: a 2013 court case, known as OSGATA vs Monsanto.

lawsuits against farmers for inadvertent contamination

Organic Seed Growers and Trade Association et al. v. Monsanto Company

Most of the information from this section is from the United States Court of Appeals for the Federal Circuit court documents.

In 2013, a coalition of organic farmers, seed distributors and anti-GMO organizations, including names such as the Center for Food Safety, Food Democracy Now!, and the Cornucopia Institute, joined forces and took Monsanto to court to invalidate 23 of the company’s patents, particularly surrounding Round-Up Ready seeds. The case is known as OSGATA v Monsanto. The case’s background states that these groups do not want to use/sell transgenic seeds or glyphosate. However, their concern is that if they do become contaminated they could “be accused of patent infringement by the company responsible for the transgenic seed that contaminates them”.

The intro to the court document explains that in 2011, Organic seed growers went before a judge in the Southern District of New York asking that the patents be judged “invalid, unenforceable, and not infringed”. They claimed that they had started growing conventional produce since the threat of contamination from GMO was so high. They had to take expensive precautions such as creating a buffer zone, so that they wouldn’t be sued by Monsanto. One grower testified to the fact that the only reason why he grows conventional seeds is the threat of a lawsuit from Monsanto, and if this threat didn’t exist then he would go back to growing organic seeds. So, in April 2011, these growers requested Monsanto to “expressly waive any claim for patent infringement [Monsanto] may ever have against [appellants] and memorialize that waiver by providing a written covenant not to sue.” OSGATA, et al claimed that they felt at risk of being sued by Monsanto if their fields were ever found to be contaminated with Monsanto’s patented GMOs.

At the heart of the issue was the fact that Monsanto’s promise to never sue a farmer whose fields have been (unknowingly) contaminated by their seeds was a statement on the company website. It wasn’t a law. It wasn’t something that they had sworn to under oath. It was just something on their webpage which, at the end of the day, could be false advertising or a PR gimmick. In back-and-forths between lawyers, Monsanto wrote that they have no reason to go after farmers for low level contamination because there’s no financial incentive, and that if the motives of the growers/farmers is true (i.e. that they don’t intend to use/sell transgenic seeds), then their fear of a lawsuit is unreasonable. The judge in the district court threw out the case in 2011 based on the fact that “these circumstances do not amount to a substantial controversy and . . . there has been no injury traceable to defendants”.

The case then went to the United States Court of Appeals for the Federal Circuit, whose court documents are the ones I’m summarizing. The discussion states that it isn’t sufficient to demonstrate that a patent is owned by someone and that there’s a risk of infringement: you have to actually demonstrate that there’s a substantial risk that harm may occur or that they have to go through expenses/costs to mitigate those risks. In other words, the judge asked the organic growers/seed distributors to demonstrate that there was the possibility that they might get sued for inadvertent contamination.

The 2 pages of appellants in the lawsuit in the OSGATA case
The 2 pages of appellants in the lawsuit in the OSGATA case

The Organic growers/seed distributors (OSGATA) conceded that Monsanto had never threatened to sue them. OSGATA stated that their fear is based on the fact that Monsanto has taken 144 growers/sellers to court and settled 700 additional cases out of court. Monsanto argued that none of these cases have been due to inadvertent contamination, and consequently, it was not equivalent to suing for inadvertent contamination.
However, the court conceded that given the way patent laws are written, even using a small amount of a patented material without authorization could constitute patent infringement. For the purposes of the appeal, the judge proceeded with the ruling based on the assumption that inadvertent contamination, including cross-pollination, was inevitable (the court document clarified that this was an assumption, not a ruling).

The documents state that the whole argument was moot if Monsanto really didn’t intend to sue: the Supreme Court has recognized that a covenant not to sue nullifies a controversy between parties. Since Monsanto had a written policy on their website against inadvertent contamination, the court documents recorded Monsanto’s position on this whole argument. Monsanto and the organic growers agreed that “trace amounts” meant approximately 1% contamination. The ruling states that although this was not a covenant not to sue, it had a similar effect and constituted a judicial estoppel, which means that Monsanto could no longer contradict something that’s been established as truth by itself and by the court.

OSGATA stated that Monsanto’s refusal to provide a covenant had a “chilling effect” and that farmers/growers would have to forgo the activities that they would have otherwise liked to pursue. The judge stated that a “chilling effect” wasn’t something tangible, that the appellants needed to have something more specific than that, and that the future harm described was speculative and hypothetical.

The court ruling ends with this statement in the concluding paragraph: “the appellants have alleged no concrete plans or activities to use or sell greater than trace amounts of modified seed, and accordingly fail to show any risk of suit on that basis. The appellants therefore lack an essential element of standing.”

Conclusion

The organic movement considered this case to be a partial victory because they now had in writing that Monsanto would never sue them for inadvertent contamination. But I’m not sure I understand this… I think you’d have to be so paranoid about what Monsanto might do that you’d be willing to incur massive legal fees to make sure that a hypothetical never happens, even when you can’t produce proof that it might.

So how is it that this myth about Monsanto suing farmers still circulates? Based on the movie “David vs Monsanto” described in part two of the series, you could believe that Monsanto plants evidence and works with testing companies to ensure that you your testing is >1%. You could believe that the 700 court cases that were settled out of court were against farmers who were inadvertently contaminated, but just didn’t have the money to fight Monsanto in court. You could also believe that all the court cases had judges and witnesses who were paid off by Monsanto.

My perspective on this is that Monsanto is a huge company that has better things to do than to sue the small farmer who inadvertently uses their seeds. From a practical perspective, it would probably represent a greater expense to them in legal fees than what they would recoup through the settlement or a court case. As I described in the last post, even in cases where Monsanto has taken farmers to court for knowingly using Monsanto seeds without an agreement, there have been massive amounts of negative publicity for the company. Imagine the uproar if they took a farmer to court who genuinely had no idea that his/her field was contaminated.

To conclude this series, I have found no evidence that farmers are sued by Monsanto for inadvertent contamination. The lawsuits that I examined were for cases where farmers knowingly and admittedly used Monsanto seeds without licensing contracts. The fact that seeds are patented is not exclusive to GMOs: as outlined in the first post, many other traditionally bred seeds are patented. For some seeds, both genetically engineered and traditionally bred, farmers sign annual contracts with seed developers. However, farmers have many choices and in no way are forced to plant these seeds or sign these contracts.

William Saletan on GMO myths in Slate

GMO Labels, by Slate staff
GMO Labels, by Slate staff

On Wednesday, Slate published a long, in-depth feature article on GMO labeling by William Saletan called Unhealthy Fixation. It has been the talk of the week in the social media discussion about genetically engineered crops and the arguments and tactics of the organizations and individuals who oppose their use. Continue reading “William Saletan on GMO myths in Slate”

Skeptics Ask Monsanto

Around the world there are “Skeptics in the Pub” events that gather folks from the local community who are interested in issues of science, technology, health, and sometimes explore the more ephemeral things like the paranormal – ghost busting and Bigfoot sorts of discussions might ensue. You should look around and see if there are folks in your area that host these evenings, and you’ll find folks interested in hearing about and discussing these wide-ranging and fascinating topics, with beer or cider or perhaps a soda. Personally, I hang around at the Boston Skeptics events, but these exist world-wide. Look for one around you. They are fun and interesting and can help support local venues.
Earlier this year I asked if the Boston Skeptics would be interested in hearing about GMOs – but from the Monsanto side. Like good skeptics, they were open to hearing this side of a controversial topic, even if they didn’t quite agree on the issues. I had met a neighbor of mine who works at the Cambridge MA Monsanto labs, Larry Gilbertson. And he was willing to present at the pub. With all agreed, we set it up for an evening of conversation. Continue reading “Skeptics Ask Monsanto”

A look at GMO policies in different nations

In the debate surrounding GMOs, a statement that is often made is that many countries have banned transgenic crops, which suggests that they are not safe. Here’s an example from the Non-GMO Project’s website:

Most developed nations do not consider GMOs to be safe. In more than 60 countries around the world, including Australia, Japan, and all of the countries in the European Union, there are significant restrictions or outright bans on the production and sale of GMOs.”

All countries have laws and regulations surrounding biotech crops, including the United States, which is why you can’t develop a transgenic crop and have it sold in stores the following season. Very few countries have an outright ban, where GMOs can neither be grown nor imported. According to GMOAnswers.com, only Kenya falls in this category, but I also found that Peru has a 10-year ban on the use and import of GMO seeds.
Continue reading “A look at GMO policies in different nations”

Medical Doctors weigh in on Glyphosate Claims

novella2
Dr. Steven Novella

Before the Holidays, a claim was being circulated around about glyphosate – the active ingredient in Roundup herbicide. The claim is that half of all children will be autistic by 2025 – and the source for this claim is none other than Dr. Stephanie Seneff. Long-time readers of this blog will recognize that she has made many claims about GMOs – in particular the Roundup herbicide that is sprayed on them – which have been addressed many times before. Is there any merit to this claim? Two highly-regarded blogging medial doctors have weighed in on this issue with a resounding no. Dr. Steven Novella, who writes at Science-Based Medicine, and the pseudonymous Orac a.k.a. Dr. David Gorski, who writes at Respectful Insolence, both evaluated Dr. Seneff’s claims and found them to be based on poor logic, bad science, and straight-up falsehoods – and completely wrong. Continue reading “Medical Doctors weigh in on Glyphosate Claims”

Review of “Complete Genes May Pass from Food to Human Blood”

The 2013 PLoS One article Complete Genes May Pass from Food to Human Blood is often used as evidence that genes from GMO can “transfer” into our bodies (such as in this article from Collective Evolution). In this post, I’d like to review the paper with you and discuss this nightmare-inducing scenario. Continue reading “Review of “Complete Genes May Pass from Food to Human Blood””

The day I unwittingly became a pro-science activist

Written by Jeff Fountain

fun facts
What kinds of Fun ‘Facts’ Fester in yonder tent? Credit: Jeff Fountain

Early this September I attended the National Heirloom Expo in Santa Rosa.  It’s an event that’s centered around the pure food movement, heirloom vegetables, and anti-GMO activism.  The speakers included Joseph Mercola, Jeffrey Smith, Andrew Kimbrell, and my personal favorite pseudoscientist, Vani Hari, a.k.a. the Food Babe.  For those unfamiliar with Food Babe, she is an anti-GMO, pro-organic public figure who attacks food and agricultural companies for what are essentially harmless practices.  The reason I mention her is because she inspired me to start my own Facebook parody page called Food Hunk, which is what sort of drove my foray into ‘activism’.  Food Hunk is to Food Babe, what Stephen Colbert is to Bill O’Reilly.  I joined a community of other wonderful Food Babe critics such as Chow Babe and Science Babe, with my page being a bit of a broader commentary on fallacious ways of thinking, such as the all-too-common naturalistic fallacy.
I’ve been interested in science all of my life, but only in the last few years have I become more involved with skepticism and the idea that you don’t need to be a scientist to think like a scientist.  As usually proliferated on social media, a constant barrage of anti-GMO fear mongering flooded my Facebook feed on a daily basis. I started trying to counter these claims with sound science.  Because many of those spreading erroneous info were good friends, I felt compelled to actually know what I was talking about and inform them, instead of simply calling them out their ignorance.  I became active in various online forums devoted to exploring the issue of genetic engineering, and found myself learning from some of the best science communicators on the topic.  Upon realizing that I couldn’t learn enough, I decided to go back to school and learn about biotechnology.  I’d recently left my fifteen-year career working in the wine industry and was exploring my passion for science.  My wife found a certificate program at CCSF called Bridge to Biosciences where I am enrolled today.  I am nowhere near as educated as many of the people I correspond with about science, but I’m always trying to learn and never pretend to wield knowledge I don’t have.  In my opinion, this is one of the most important components of skepticism.  If more people only stopped pretending to know what they do not know, we wouldn’t see the blatant misinformation that so predominantly surrounds the topic of GMOs.
Recently I was in a GMO enthusiast forum, when I noticed a post from Karl at Biology Fortified.  He mentioned the Heirloom Expo and was asking if anyone from the Bay Area was going to attend.  Santa Rosa is only about an hour from where I live, and so after realizing I didn’t really have anything planned for the day I thought, “How could I possibly pass up the opportunity to introduce Food Hunk to Food Babe?”  I put on my ‘I love GMOs’ t-shirt, (carefully concealed under my sweatshirt) and hit the road to Santa Rosa. Continue reading “The day I unwittingly became a pro-science activist”

GM Watch finds GENERA useful, “badly needed”

Editor’s note: See an update at the bottom about GM Watch’s response to this post.
In a discussion about the scientific literature on genetically engineered crops, Claire Robinson of GM Watch has previously said: “I am, as you say, unaware of your GENERA project. A comprehensive list of studies on all aspects of GMOs is badly needed but beyond our means to gather together.” Biology Fortified, Inc., with our limited resources and volunteer staff, have come to the rescue and created this “badly needed” resource. Happily, GM Watch is now aware that GENERA is in beta testing, with more to come.
In response to our recent press release about the beta test of GENERA, Claire Robinson tried the resource out, and found it useful. She was able to use GENERA to search for literature, find the information she wanted, and she agreed with our evaluation of the scientific literature in at least two cases, as discussed in a post published on GM Watch* in response to our press release about GENERA. Although she thought it both needed and useful, the GM Watch post took an odd tone in the form of a criticism – claiming that we were misrepresenting the research contained in GENERA and leaving out important information. There were so many misunderstandings in Ms. Robinson’s post that I wanted to help her organization understand what it all means and clear up their confusion. Continue reading “GM Watch finds GENERA useful, “badly needed””

Are Neonicotinoids the Sole Factor Responsible for Colony Collapse Disorder?

5905532828_06a14b450c_z
Frank explores a bee hive. Credit: KJHvM. See the whole album here.

A recent paper published in The Bulletin of Insectology claiming that neonicotinoids are the sole cause of CCD has been circulating in the media. The author, Chensheng Lu, has a history of doing research that makes spurious claims about the relationship between CCD and a specific group of pesticides. In this post, I am going to discuss Lu’s research, and use it as a stepping stone to discuss the role that pesticides play in honeybee health.

Why are honeybees exposed to pesticides?

Bees are insects which are raised as livestock, and kept around farms in order to pollinate crops. In order to combat mites which damage adults and spread diseases, beekeepeers use a variety of pesticides. The two most widely used are a pyrethroid called Fluvalinate and an organophosphate called Coumaphos. It is easy to forget that we treat these mites with insecticides, and many popular media reports neglect to mention this completely and instead focus on the agricultural pesticide angle. However, Fluvalinate and Coumaphos are found in virtually all pollen and wax samples. They are frequently found with chlorotalonil, which will synergize the activity of pyrethroids. Coumaphos is the only pesticide found more frequently in non-CCD afflicted colonies. These pesticides are an important part of the honeybee health story. Continue reading “Are Neonicotinoids the Sole Factor Responsible for Colony Collapse Disorder?”