110 Nobel Laureates to Greenpeace: Change Your Stance on GMOs

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Sir Richard Roberts, Nobel Laureate in Physiology or Medicine (1993), opened the press conference asking Greenpeace to reverse its stance on genetically engineered crops. Credit: Jenny Splitter

More than 100 Nobel Laureates are calling on Greenpeace to reconsider its opposition to GMOs. Yesterday, representatives of the group of Nobel Laureates, Sir Richard Roberts, Professor Martin Chalfie and Professor Randy Schekman held a press conference at the National Press Club to explain why 110 Nobel Laureates came together now to support transgenic crops and ask Greenpeace to reverse its long-held stance against GMOs. Continue reading “110 Nobel Laureates to Greenpeace: Change Your Stance on GMOs”

Better Know a Scientist: Rice Research Scientist Dr Nir Oksenberg

In this month’s “Better Know a Scientist”, I’m interviewing Dr Nir Oksenberg. He works in a lab that actually makes transgenic crops! Nir’s career seems to have taken a very windy road: he completed his PhD at UCSF studying a gene implicated in autism, but is doing his post-doc in Dr Pamela Ronald’s lab at UC Davis (if you aren’t familiar with Dr Pamela Ronald, please view her TED talk or her book “Tomorrow’s Table”. Her book is a fantastic read for anyone interested in learning about genetically modified crops and organic food). We “met” over the internet, when he kindly sent me an encouraging email on one of my articles. I have yet to take him up on his offer of visiting the lab in Davis, mostly because my kid would probably knock over someone’s research project or trample on a crop that took a few years to make.
Continue reading “Better Know a Scientist: Rice Research Scientist Dr Nir Oksenberg”

Thoughts About Norm Borlaug for his 100th Birthday

Written by Steve Savage. Graphs by Steve, based on FAO and Geohive data.

Norman Borlaug would have been 100 years old last week.  He has been called “The Man Who Fed The World,” and “The Father of The Green Revolution.”  Norm Borlaug was the first plant pathologist to be awarded a Nobel Prize (1970) – for contributions to world peace. For all of use who are fellow plant pathologists, his work has been particularly inspiring.

It is a good time to look back at how the challenge of feeding the world population was met during Borlaug’s career, because we have a similar challenge ahead of us. The chart below shows global population from 1950 with a projection to 2100.  I’ve been looking at food production data available from the UN Food and Agriculture Organization (FAOSTAT).  If we look at the half century since FAO started tracking it in 1960,  global population increased by 3.89 billion.  Between 2010 and 2060, global population is projected to rise by another 3.04 billion.

Between 1960 and 2010, production of most crops did manage to keep up with population growth and for many crops there was actually more available per person in 2010 than in 1960.  Living standards also improved in many parts of the world, which meant that people were able to enjoy that per capita increase.  Fertility rates have declined with the education of women combined with improvements in living standards and food security. It is projected that global human population will level off by around 2100 due to these factors.

The increase in food production during Borlaug’s era was mostly achieved through increased yield on each acre or hectare grown, not from farming more land.  That was made possible by agronomic improvements,  including the breeding advances that came from the work of Borlaug and many others.

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In the graph above, the two bottom, green bars show the global crop area in the window 1960-65 (1.09 billion hectares) and 2005-10 (1.45 billion hectares).  The increase, shown in the red bar, is 362 million hectares. That is an enormous amount of land, but without increased yield, it would have taken nearly 3.1 billion hectares (blue bar) to have provided the amount of food that was available to the world by 2010.  That effectively means that the global farming community, and those that aided it with technologies, advice and expertise, “saved” more than 1.6 billion hectares of land from being converted from a natural state into farmland.  Realistically, there is not that much land which could ever be farmed.

Many of Borlaug’s contributions were to the staple food crop – wheat.

Wheat is not a single crop, but a collection of many different types of wheat grown for different kinds of food ranging from hearty breads, to pasta, to crackers, to flat breads to soft noodles. By the end of this 50 year window, the world’s wheat farmers were producing 2.69 times as much wheat as in 1960. However, 97% of that increase (green part of the bar) was enabled by higher yields.  Only 10 million more hectares were being grown. That meant that the world could continue to have enough wheat without the need for adding 346 million more wheat hectares.  That is the legacy of Borlaug and the other participants in the Green Revolution.

The story with rice is almost as positive.  In 2005-10, humanity had access to 2.9 times as much rice as in 1960-65, and 83% of the increase was attributable to yield with 39 million new hectares added.  That meant that there were 187 million hectares which did not need to be added to the rice production base.

The story behind these higher yields is complex and varies across geographies. The details of how we might continue this sort of progress through 2060 are also complex and will involve new challenges such as climate change.  Even so, on this important anniversary it is fitting to look back at the remarkable accomplishments of the past to find inspiration for the challenges of the future.  Let us hope that at the 150th anniversary of Norm Borlaug’s birth people will once again be able to look back and tell this kind of story.  A story about humanity continuing to be fed, but without having had to add much if any new farmed land.  Even into his 90s, Borlaug continued to be an articulate proponent for letting farmers use the full toolbox of technologies, including biotechnology, to pursue such goals.  Now it is up to us to continue to make that case.

Written by Guest Expert

Steve Savage has worked with various aspects of agricultural technology for more than 35 years. He has a PhD in plant pathology and his varied career included Colorado State University, DuPont, and the bio-control start-up, Mycogen. He is an independent consultant working with a wide variety of clients on topics including biological control, biotechnology, crop protection chemicals, and more. Steve writes and speaks on food and agriculture topics (Applied Mythology blog) and does a bi-weekly podcast called POPAgriculture for the CropLife Foundation.

So Much for My Favorite 2012 Paper

Written by Kevin Folta

Republished from Illumination.
Ask any scientist what papers truly intrigued or inspired them.  All of us have a few.
One of my favorites hit Cell Research back in summer of 2012.  In this paper, Zhang et al claimed that dietary microRNAs from rice were somehow ushered through the digestive gauntlet and modulated physiologically relevant changes in LDL, at least in mice.  MicroRNAs are a relatively recent regulatory regimen, a monkey wrench in the central dogma in of molecular biology.  These tiny runs of a 1-2 dozen nucleotides interact with RNA, leading to its degradation. They interact with RNA to change translation and bind to DNA to inspire transcriptional control.  In other words, they place a new layer of complexity into a complex process.
We know that there are 1000+ microRNAs in the human genome and probably just as many in plants.  The work by Zhang was so cool because it said that RNAs from plants could have effects on mammalian physiology.  Mice fed rice experienced changes in gene expression in their livers, apparently imparted by microRNA. It seemed consistent with what we knew about plants and their effects on blood lipoprotein levels.  The paper was really slick– it was exciting to read.
But as I reached the end I could not help but feel the skepticism oozing in.  A little back-of-the-envelope math would reveal that even with liberal estimates there’s no way that a single species of plant microRNA could be present at high enough concentrations to get through postharvest treatment, cooking, digestion, transport, and all of the other hurdles to make the process work as proposed.
The numbers I calculated were ridiculously low, impossible!
But science does have surprises.  I talked about this paper in a journal club with graduate students and remember saying, “When it is repeated or expanded, then we could get excited.”
Of course, the anti-GMO world ignited. Continue reading “So Much for My Favorite 2012 Paper”

KQED Quest on GMOs

KQED Quest, based in San Francisco, has just posted a half-hour special on GMOs called Next Meal: Engineering your Food, by Gabriela Quirós. In the wake of proposition 37 in California there has been a lot more public awareness of genetically engineered crops, but little public education about it. (Just think what those millions spent could have accomplished) So in this special KQED Quest takes a look at the science of plant breeding and genetic engineering, interviewing Peggy Lemaux from UC Berkeley, Eduardo Blumwald at UC Davis, along with a host of other farmers, writers, and activists. I have been anticipating this special for some time, because I’m in it! Well, sort of. Continue reading “KQED Quest on GMOs”

Live Tweeting Golden Rice – Storified

Hi everyone, Frank N. Foode™ here. I was hanging out, smelling some Tulips in Madison, WI, and none other than Dr. Michael Grusak stopped by from the Baylor College of Medicine to give a seminar on his nutritional research into Golden Rice. I was so excited I ended up live tweeting the whole thing on #mikegrusak! For those who aren’t big on the whole twitter thing – have no fear – I Storified it and added in some pictures and extra links, too. Now a seminar that reached dozens can now be experienced by hundreds, or thousands. (Isn’t technology wonderful?)
So does a genetically engineered variety of rice made by hundreds have the potential to help thousands, or maybe millions? Check this out! Continue reading “Live Tweeting Golden Rice – Storified”

Why did The Atlantic publish this piece trying to link miRNAs and GMOs?

Editor’s note: republished with permission from The Biology Files.
By Emily Willingham

Rice.

A study from a Chinese group led by Chen-Yu Zhang of Nanking University and published in Cell Research, has uncovered the fascinating result that when people eat rice, they can absorb microRNAs (miRNAs)–tiny sequences of RNA–from the rice into the blood. These rice-originating miRNAs turn up in blood and tissues of people who eat rice and…here’s the kicker…one type of rice miRNA interacts with human proteins that are responsible for removing LDL (“bad” cholesterol) from the blood (!). It’s the first report of plant miRNAs ending up in people by way of diet and the finding that at least one of them alters an important process in the body.
The implications could extend in many a direction, but not as far as writer Ari Levaux would like to take them in this remarkably confusing article published on the Atlantic Website. Before taking on the errors and the overstretch that are that piece, let’s look at something far more interesting: miRNAs themselves. Continue reading “Why did The Atlantic publish this piece trying to link miRNAs and GMOs?”